Endocrine Abstracts

Background: The purpose of this study was to register the frequency and cause of method-dependent interference in the Roche thyroid immunoassays observed in our laboratory.Methods: Serum samples to confirm discordant thyroid results were collected from June 2013 to September 2018, in samples sent to the Hormone Laboratory, Oslo University Hospital. The laboratory serves as a reference laboratory on thyroid diseases for about 2/3 of the inhabitants of Nor...

Objective: Immunoassays of steroids are still used in the diagnosis and biochemical monitoring of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21 OHD). However, high levels of steroid intermediates can promote cross-reactivity between steroids giving rise to falsely elevated levels.Design: Fifty-nine patients with classic 21OHD (38 women) were studied. Blood samples were collected in the morning after overnight medicatio...